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A novel algorithm is presented for classification of four patterns of diffuse lung disease: normal, emphysema, honeycombing and ground glass opacity, on the basis of textural analysis of high resolution computed tomography (HRCT) lung images. The algorithm incorporates scale-space features based on Gaussian derivative filters and multi-dimensional multi-scale features based on wavelet and contourlet...
The utility of 18F-deoxyglucose (18F-FDG) in oncology, cardiology, and neurology has generated great interest in a more economical ways of imaging 18F-FDG than conventional PET scanners. The main thrust of this work is to investigate the potential use of LaBr3:Ce materials in a low-cost FDG-SPECT system compared to NaI(Tl) using GATE Monte Carlo simulation. System performance at 140 keV and 511 keV...
Experimental studies of pro-arrhythmic mechanisms are scarcely performed in humans due to the limited availability of human cardiomyocytes. Subsequently, extrapolation of animal experimental research to humans is widely extended. Our aim is to systematically compare the ionic mechanisms of the main cellular biomarkers of arrhythmic risk between human and rabbit using computer simulations. For this...
An automatic Uni- or Multi-modal Intelligent Seizure Acquisition (UISA/MISA) system is highly applicable for onset detection of epileptic seizures based on motion data. The modalities used are surface electromyography (sEMG), acceleration (ACC) and angular velocity (ANG). The new proposed automatic algorithm on motion data is extracting features as “log-sum” measures of discrete wavelet components...
Parallel excitation using coil array has been introduced in MRI as an effective method to design multi-dimensional spatially selective RF pulses. Generally, all transmit coil elements are used simultaneously in parallel excitation. In case of large array, RF pulse design requires significant computation time and memory size. In this paper, a method using reduced number of coils for parallel excitation...
A 1.8-mW, 18.5-mm2 64-channel current readout ASIC was implemented in 0.18-μm CMOS together with a new calibration scheme for silicon nanowire biosensor arrays. The ASIC consists of 64 channels of dedicated readout and conditioning circuits which incorporate correlated double sampling scheme to reduce the effect of 1/f noise and offset from the analog front-end. The ASIC provides a 10-bit digital...
A novel approach is proposed for generating data driven models of the lung nodules appearing in low dose CT (LDCT) scans of the human chest. Four types of common lung nodules are analyzed using Active Appearance Model methods to create descriptive lung nodule models. The proposed approach is also applicable for automatic classification of nodules into pathologies given a descriptive database. This...
In this paper a new non-invasive method for screening patients with obstructive sleep apnea (OSA) during wakefulness is proposed. Eight people with OSA and eight non-apneic individuals participated in this study. The tracheal breath sound was recorded in supine and upright positions during both nose and mouth breathing maneuvers. Spectral analysis of the respiratory sound signals showed the variation...
This study aims to investigate the measurement performance on different sensor deployment and to determine the optimal position for monitoring heart rate (HR) and respiration rate (RR) during sleep. Five identical sensor boards were deployed on different positions simultaneously during sleep to detect changes of applied pressure due to heart beating and breathing. One board was set beneath the pillow;...
Detachment of greater trochanter (GT) is generally associated with hip arthroplasty complications and needs for repositioning and fixation. A new GT reattachment system (Y3) was proposed to reduce GT displacements in anterior-posterior direction to decrease non-union issues. The goal of this study is to develop and validate a FEM of the Y3 GTR system. FEM validation suggests a good concordance between...
This paper describes the detection of preictal bursting using wavelet transform application and cross-correlation analysis. The wavelet transform is applied to data reduction and signal pre-processing. The extracted features provide simplified signals to process by means of the cross-correlation technique. The algorithm has been tested with a set of preictal data, interictal data and spontaneous crises,...
Closed/Open angle glaucoma classification is important for glaucoma diagnosis. RetCam is a new imaging modality that captures the image of iridocorneal angle for the classification. However, manual grading and analysis of the RetCam image is subjective and time consuming. In this paper, we propose a system for intelligent analysis of iridocorneal angle images, which can differentiate closed angle...
In this paper, we present a novel method of analyzing retinal vasculature using Fourier Fractal Dimension to extract the complexity of the retinal vasculature enhanced at different wavelet scales. Logistic regression was used as a fusion method to model the classifier for 5-year stroke prediction. The efficacy of this technique has been tested using standard pattern recognition performance evaluation,...
Heart Rate variability (HRV) is important in characterizing heart functions. However, artifacts and trends are regularly observed to contaminate the HRV sequences. This study proposes a simple and effective preprocessor for the removal of artifacts and trend in the HRV sequences. A thresholding filter is applied to remove artifacts to maintain the HRV sequences in a reasonable range. A wavelet filter...
The present work introduces a new ECG delineator, based on the Phasor Transform, which is characterized by its robustness, low computational cost and mathematical simplicity. The method converts each instantaneous ECG sample into a phasor, thus being able to deal very precisely with P and T waves, which are of notably lower amplitude than the QRS complex. Initially, the method relies on the detection...
Most of the studies on the synchronization between EHG signals, recorded during the same contractions at different locations, are limited to the use of only two channels. Multichannel techniques have however been widely applied to EEG signals but rarely to EHG. In this paper, we investigate the use of multichannel uterine EMG signals for classifying contractions. We compare the performance of phase...
In this paper, we present an automatic method for K-complexes detection based on features extraction and the use of fuzzy thresholds. The validity of our process was examined on the basis of two visual K-complexes scorings performed on 5 excerpts of 30 minutes. Results were investigated through all different sleep stages. The algorithm provides global true positive rates of 61.72% and 60.94%, respectively...
Hypoglycaemia is a serious side effect of insulin therapy in patients with diabetes. We measure physiological parameters (heart rate, corrected QT interval of the electrocardiogram (ECG) signal) continuously to provide early detection of hypoglycemic episodes in Type 1 diabetes mellitus (T1DM) patients. Based on the physiological parameters, an evolved fuzzy reasoning model (FRM) to recognize the...
In this paper, we proposed a tunnel morph model for bio-signal waveform in measuring their similarity. Firstly, the formal specifications of bio-signal waveforms are given. And then, a series of model establishing related definitions are presented. These definitions contain waveform segmentation; waveforms distance measurement, and tunnel width computation. Moreover, on the base of the model, a similarity...
High Density surface Electromyography (HDsEMG) has been applied in both research and clinical applications for non-invasive neuromuscular assessment in several different fields using 2-D array. Proper interpretation of HDsEMG signals requires identifying “good” channels (where there is no short-circuit or bad-contact or major power line interference problem). Recording with many channels usually implies...
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