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k-t PCA is a regularized image reconstruction method to recover images from highly undersampled dynamic magnetic resonance data. It is based on the decomposition of the training and the undersampled data into temporally and spatially invariant terms using principal component analysis. In this paper, a compartment-based k-t PCA reconstruction approach is presented, with the objective of improving highly...
Three-dimensional optical coherence tomography (OCT) is a new ophthalmic imaging technique offering more detailed quantitative analysis of the retinal structure. Eye movement during 3D OCT scanning, however, creates significant spatial distortions that may adversely affect image interpretation and analysis. Current software solutions must use additional reference images or B-scans to correct eye movement...
A three-dimensional anatomically and electro-physiologically realistic model of atrial propagation is developed utilizing generic cardiac ionic models fitted to experimentally recorded action potentials (APs). The atrial geometry incorporated realistic wall thickness and twelve anatomical structures, including the sino-atrial node (SAN), pulmonary veins, interatrial septum, Bachmann's bundle and coronary...
Hepatic vessel structure is very important to ensure the blood supply of the liver tissue. Therefore the knowledge of the hepatic vessel system is indispensable in liver surgery planning, for example before performing a liver resection. The purpose of this paper is to present an easy to use and fast method concerning hepatic vessel segmentation and risk analysis, which is intended to be applicable...
Annulus manual segmentation is an important tool for the study of valve anatomy and physiology, for the four main valves of the heart (mitral, tricuspid, aortic and pulmonary). In this paper we review two traditional manual segmentation approaches: slice-by-slice and interpolating a sparse set of landmarks with a spline curve. We propose a new Spline Tool for the open source software platform Seg3D,...
The slice intersection motion correction (SIMC) method is a powerful tool to compensate for motion that occurs during in utero acquisition of the multislice magnetic resonance (MR) images of the human fetal brain. The SIMC method makes use of the slice intersection intensity profiles of orthogonally planned slice pairs to simultaneously correct for the relative motion occurring between all the acquired...
The Compact Lightweight Surgery Robot from the University of Hawaii includes two teleoperated instruments and one endoscope manipulator which act in accord to perform assisted interventional medicine. The relative positions and orientations of the robotic instruments and endoscope must be known to the teleoperation system so that the directions of the instrument motions can be controlled to correspond...
The paper proposes a novel Extensible Markup Language (XML) based format called ART-ML that aims at supporting the interoperability and the reuse of models of blood flow, mass transport and plaque formation, exported by ARTool. ARTool is a platform for the automatic processing of various image modalities of coronary and carotid arteries. The images and their content are fused to develop morphological...
In clinical routine of liver surgery there are a multitude of risks such as vessel injuries, blood loss, incomplete tumor resection, etc. In order to avoid these risks the surgeons perform a planning of a surgical intervention. A good graphical representation of the liver and its inner structures is of great importance for a good planning. In this work we introduce a new planning system for liver...
Left ventricular hypertrophy (LVH) is a complex cardiac condition mainly identified by the thickening of the myocardial wall. Although most of the contemporary cardiac imaging modalities provide high resolution 3D images, the wall thickness (WT) is still measured within the acquired planes. This way of measurement may introduce an error as cardiac wall is not necessarily orthogonal to the plane. In...
We present a new technique to delineate lumen borders in intravascular ultrasound (IVUS) volumes of images acquired with a high-frequency Volcano (Rancho Cordova, CA) 45MHz transducer. Our technique relies on projection of IVUS sub-volumes onto orthogonal directional brushlet functions. Through selective projection of IVUS sub-volumes images and their Fourier transforms, tissue-specific backscattered...
The work reported in this paper aimed at developing and testing an automated method to calculate the biodistribution of a specific PET tracer in mouse brain PET/CT images using an MRI-based 3D digital atlas. Surface-based registration strategy and affine transformation estimation were considered. Such an approach allowed overcoming the lack of anatomical information in the inner regions of PET/CT...
Stanford type B aortic dissections (TB-AD), which split the descending aorta in a true and false lumen, have better in-hospital survival than type A dissections affecting the ascending aorta. However, short-term and long-term prognosis for the individual patient remains challenging, with one in four patients not surviving after 3 years. Towards a better understanding of the influence of tear location...
This paper presents a model-based reconstruction method of the coronary tree from a few number of projections in rotational angiography imaging. The reconstruction relies on projections acquired at a same cardiac phase and an energy function minimization that aims to lead the deformation of the 3D model to fit projection data whereas preserving coherence both in time and space. Some preliminary results...
Compressive Sensing (CS) is a nascent sampling and reconstruction paradigm that describes how sparse or compressible signals can be accurately approximated using many fewer samples than traditionally believed. In magnetic resonance imaging (MRI), where scan duration is directly proportional to the number of acquired samples, CS has the potential to dramatically decrease scan time. However, the computationally...
Cranioplasty is a commonly performed procedure. Outcomes can be improved by the use of patient specific implants, however, high costs limit their accessibility. This paper presents a low cost alternative technique to create patient specific polymethylmethacrylate (PMMA) implants using rapid prototyped mold template. We used available patient's CT-scans, one dataset without craniotomy and one with...
The paper describes a set of approaches and routines designed to improve results in CT based 3D subtractive angiography of lower extremities via better global locally defined image data registration. Starting from the generic concept of 3D disparity-based flexible registration, modifications of this idea are made founded on prior anatomical knowledge, as segmentation into individual bone areas, their...
A method is proposed for 3-D reconstruction of coronary from a limited number of projections in rotational angiography. A Bayesian maximum a posteriori (MAP) estimation is applied with a Poisson distributed projection to reconstruct the 3D coronary tree at a given instant of the cardiac cycle. Several regularizers are investigated L0-norm, L1 and L2 -norm in order to take into account the sparsity...
Catheter based radio frequency ablation of atrial fibrillation requires real-time 3D tracking of cardiac surfaces with sub-millimeter accuracy. To best of our knowledge, there are no commercial or non-commercial systems capable to do so. In this paper, a system for high-accuracy 3D tracking of cardiac surfaces in real-time is proposed and results applied to a real patient dataset are presented. Proposed...
This paper describes and assesses for the first time the use of a handheld 3D laser scanner for scalp EEG sensor localization and co-registration with magnetic resonance images. Study on five subjects showed that the scanner had an equivalent accuracy, a better repeatability, and was faster than the reference electromagnetic digitizer. According to electrical source imaging, somatosensory evoked potentials...
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