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The development of a cell based biochip-sensing platform that examines the effects of toxic chemicals both electrically and optically is presented. The name of this sensing platform is called Toxichip. Toxichip aims to develop and promote alternative novel in-vitro testing methods for the monitoring of a vast array of toxins, thus alleviating the current demand for animal sacrifice while also permitting...
Biomedical signals are customarily overlaid with interferences and noise, furthermore, baseline wandering is another significant drawback to their accurate interpretation, especially if the implementation platform is a wheelchair. The nonlinear processes which generate the physiologic signals, and the disturbances, regularly exclude, or limit, the usage of classical linear techniques, hence, among...
The aim of this study is to develop a method for measuring the respiratory waveform using non-contact electrodes during bathing. To determine the most appropriate electrode arrangement, we modeled a composite system consisting of a body submerged in bath water. We calculated the frequency dependence of the impedance amplitude using a three-dimensional finite difference method (3D-FDM). The simulation...
Gastric impedance spectroscopy has been proposed as a method of monitoring mucosal injury due to hypoperfusion and ischemia in the critically ill. During validation tests for this procedure, it was found that 60% of the measurements had errors by factors inherent to the clinical setting, indicating that some kind of automatic error detection should be incorporated to potentially avoid the loss of...
A new drip infusion solution monitoring system has been developed for hospital and care facility use. The system detects the fall of each drip chamber drop of fluid and also a free-flow situation. Three non-contacting copper foil electrodes are used. The electrodes are wrapped around the infusion supply polyvinyl chloride (PVC) tube from the solution bag, the drip chamber, and the infusion PVC tube...
Successful management of cardiac heart failure requires a multifactorial approaching. It has been suggested that implantable hemodynamic long-term monitoring can improve patient care. This paper presents an analysis of the hemodynamic parameters commonly recorded, the most used implantable devices and their associated clinical trials. Newly implantable miniaturized sensors and devices are revisited...
This paper analyses the use of Electrical Impedance Spectroscopy (EIS) to efficiently monitor cryoprotectant concentrations in cryopreservation protocols. The proposed technique can improve methods such as Liquidus Tracking (LT), allowing vitrification without exposing tissues to damaging concentrations of cryoprotectant at relatively high temperatures, and avoiding rapid temperature changes. This...
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