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Protein-DNA interactions play a crucial role in transcriptional regulation and other biological processes. Quantitative predictive models of protein-DNA binding affinities can increase our understanding of molecular interaction and help validate putative transcription factor binding sites or other regulatory features. Such predictive models must take into account context-specific features associated...
Classifying G protein-coupled receptors (GPCRs) is an interesting topic because of the important role of GPCRs in pharmaceutical research. GPCRs have diverse functions and are involved in many biological processes, which makes them an ideal target of novel medicine. The diverse nature of GPCRs results in the lack of overall sequence homolog among the members, making the classification of GPCRs a very...
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