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Atrial fibrillation (AF) is the most common cardiac arrhythmia. It is characterized by rapid and disorganized electrical activity in the atria. Atrial arrhythmias can be triggered from an ectopic focus, i.e., an abnormal impulse originating in an area other than the sinus node, generating reentrant waves. The regional ionic heterogeneities found in the atria cause a gradual shortening of the action...
Atrial fibrillation (AF) is the most common cardiac arrhythmia. It is characterized by rapid and disorganized electrical activity in the atria. Atrial arrhythmias can be triggered from an ectopic focus, i.e., an abnormal impulse originating in an area other than the sinus node, generating reentrant waves. The regional ionic heterogeneities found in the atria cause a gradual shortening of the action...
High frequency alternating current (HFAC) sinusoidal waveforms can block conduction in mammalian peripheral nerves. A nerve simulation software package was used to simulate HFAC conduction block in a mammalian axon model. Eight axon diameters from 7.3 mum to 16 mum were tested using sinusoidal waveforms between 1 kHz to 40 kHz. Block was obtained between 3 kHz to 40 kHz and the current threshold for...
High frequency alternating current (HFAC) sinusoidal waveforms can block conduction in mammalian peripheral nerves. A nerve simulation software package was used to simulate HFAC conduction block in a mammalian axon model. Eight axon diameters from 7.3 mum to 16 mum were tested using sinusoidal waveforms between 1 kHz to 40 kHz. Block was obtained between 3 kHz to 40 kHz and the current threshold for...
We developed user-friendly software that generates stimulation profiles by using user-customized model-based control of walking. The model is a multi-segment structure with pin and ball joints. A pair of an agonist and an antagonistic muscles acts at each joint. Each muscle is modeled by a three-compartment multiplicative model. The control is based on optimization that uses a cost function that minimizes...
We developed user-friendly software that generates stimulation profiles by using user-customized model-based control of walking. The model is a multi-segment structure with pin and ball joints. A pair of an agonist and an antagonistic muscles acts at each joint. Each muscle is modeled by a three-compartment multiplicative model. The control is based on optimization that uses a cost function that minimizes...
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