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Saving life of patients with acute life-threatening heart failure is a major challenge. One has to correct several fatal hemodynamic abnormalities at the same time within a limited time frame. The formulation of such complicated treatments enables the development of a system that can be used to save automatically lives of patients with acute heart failure, an autopilot system. To accomplish this,...
Saving life of patients with acute life-threatening heart failure is a major challenge. One has to correct several fatal hemodynamic abnormalities at the same time within a limited time frame. The formulation of such complicated treatments enables the development of a system that can be used to save automatically lives of patients with acute heart failure, an autopilot system. To accomplish this,...
We update a cardiopulmonary (CP) model previously developed by our group, more convincingly validate the model with additional hemodynamic and echocardiographic data, and demonstrate the utility of the model by extending it to the simulation of left ventricular diastolic dysfunction (LVDD) via a simple parameter change. The model has considerable potential for the characterization of complex cardiopulmonary...
We update a cardiopulmonary (CP) model previously developed by our group, more convincingly validate the model with additional hemodynamic and echocardiographic data, and demonstrate the utility of the model by extending it to the simulation of left ventricular diastolic dysfunction (LVDD) via a simple parameter change. The model has considerable potential for the characterization of complex cardiopulmonary...
Previously, we built a pulmonary and cardiovascular integrated model which is driven by O2 consumption. However this model is adjusted to average person and cannot correspond to individual difference. It needs parameter adjustment to be applied for simulation of a particular person. We used lumped parameter models, which have simple structures and are well suited to macro-model. However they have...
Previously, we built a pulmonary and cardiovascular integrated model which is driven by O2 consumption. However this model is adjusted to average person and cannot correspond to individual difference. It needs parameter adjustment to be applied for simulation of a particular person. We used lumped parameter models, which have simple structures and are well suited to macro-model. However they have...
The system which provides short-term cardiovascular regulation has a very complex structure, resulting from the non-linear interaction among several different mechanisms: they include baroreceptors, peripheral chemoreceptors, lung-stretch receptors, a direct CNS response to hypoxia and hypercapnia, local vessel response to changes in blood gas content. Furthermore, during dynamic exercise a feedforward...
The system which provides short-term cardiovascular regulation has a very complex structure, resulting from the non-linear interaction among several different mechanisms: they include baroreceptors, peripheral chemoreceptors, lung-stretch receptors, a direct CNS response to hypoxia and hypercapnia, local vessel response to changes in blood gas content. Furthermore, during dynamic exercise a feedforward...
Aneurysms are a local dilatation of a vessel wall of at least twice the normal diameter (commonly accepted definition). They are asymptomatic and rupture is often lethal. Thus, prediction of rupture is an important stake. Aiming at a diagnosis tool relying on patient specific data and general physiological values, we created a virtual aneurysm model based on real imaging data. Fluid/structure interaction...
Aneurysms are a local dilatation of a vessel wall of at least twice the normal diameter (commonly accepted definition). They are asymptomatic and rupture is often lethal. Thus, prediction of rupture is an important stake. Aiming at a diagnosis tool relying on patient specific data and general physiological values, we created a virtual aneurysm model based on real imaging data. Fluid/structure interaction...
Although many clinical techniques have been proposed to assess blood volume none have been established as an undisputed standard practice, Volume studies suggest systolic pressure variation (SPV) as a promising volume indicator but underlying influences on SPV are not well understood. Successful modeling of SPV will reveal the major SPV influencers, guide algorithm development to accommodate these...
Although many clinical techniques have been proposed to assess blood volume none have been established as an undisputed standard practice, Volume studies suggest systolic pressure variation (SPV) as a promising volume indicator but underlying influences on SPV are not well understood. Successful modeling of SPV will reveal the major SPV influencers, guide algorithm development to accommodate these...
Compared to cardiac ischemia, relatively little is known about ischemia that develops within the gastrointestinal system. The work presented here is a first step towards developing a detailed anatomically and biophysically based model of the mesenteric arterial system of the human intestine to be used to simulate normal and compromised blood flows. Data from the Visible Human project were used to...
Compared to cardiac ischemia, relatively little is known about ischemia that develops within the gastrointestinal system. The work presented here is a first step towards developing a detailed anatomically and biophysically based model of the mesenteric arterial system of the human intestine to be used to simulate normal and compromised blood flows. Data from the Visible Human project were used to...
Estimation of parallel conductance using the impedance electrode technique is usually done assuming isotropic conditions. This may not be the best solution since the myocardium is an anisotropic material. This paper exposes the effect of fiber orientation for volume measurement using a conductor model with asymmetrical source electrodes. Simulation results show calculated volumes between surrounding...
Estimation of parallel conductance using the impedance electrode technique is usually done assuming isotropic conditions. This may not be the best solution since the myocardium is an anisotropic material. This paper exposes the effect of fiber orientation for volume measurement using a conductor model with asymmetrical source electrodes. Simulation results show calculated volumes between surrounding...
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