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An accurate and rapid assay of cardiac nerve growth factor (NGF) levels in blood can provide physicians with critical information regarding myocardial injury and neural remodeling in cardiac tissues to identify patients at risk of impending heart attack, thereby enabling them to receive appropriate lifesaving treatment more quickly. Currently used assay methods, such as enzyme-linked immunosorbent...
An accurate and rapid assay of cardiac nerve growth factor (NGF) levels in blood can provide physicians with critical information regarding myocardial injury and neural remodeling in cardiac tissues to identify patients at risk of impending heart attack, thereby enabling them to receive appropriate lifesaving treatment more quickly. Currently used assay methods, such as enzyme-linked immunosorbent...
Several studies have been performed with automatic motion analysis techniques to investigated the locomotor disorders of patients with severe Parkinson's disease (PD). These are mainly related to steady-state walking. Aim of the present study was to investigate the presence and the degree of these disorders in patients at early stages of PD. For this purpose a group of patients with mild PD (H&Yles2)...
Several studies have been performed with automatic motion analysis techniques to investigated the locomotor disorders of patients with severe Parkinson's disease (PD). These are mainly related to steady-state walking. Aim of the present study was to investigate the presence and the degree of these disorders in patients at early stages of PD. For this purpose a group of patients with mild PD (H&Yles2)...
Autonomic function testing forms an integral part of physiological investigations both for human and animal research. Clinically, recent times have seen them emerging as tools in settling diagnosis in several neurological, cardiovascular, endocrinal disorders where autonomic function are compromised. The reasons for such emergence have been their simplicity, noninvasiveness, and their ability to decipher...
Autonomic function testing forms an integral part of physiological investigations both for human and animal research. Clinically, recent times have seen them emerging as tools in settling diagnosis in several neurological, cardiovascular, endocrinal disorders where autonomic function are compromised. The reasons for such emergence have been their simplicity, noninvasiveness, and their ability to decipher...
Magnetic resonance spectroscopic imaging (MRSI) is a powerful tool for diagnosis of many pathologic conditions. However conventional MRSI involves long scan times, in the order of 20 minutes. This work simulated an autocalibrating parallel technique based on GRAPPA algorithm for accelerating MRSI and applied it to 3 dimensional (3D) MRSI of the brain at 3 Tesla. Employing two fold undersampling in...
Magnetic resonance spectroscopic imaging (MRSI) is a powerful tool for diagnosis of many pathologic conditions. However conventional MRSI involves long scan times, in the order of 20 minutes. This work simulated an autocalibrating parallel technique based on GRAPPA algorithm for accelerating MRSI and applied it to 3 dimensional (3D) MRSI of the brain at 3 Tesla. Employing two fold undersampling in...
A technique for selectively activating nerve fibers based on their diameter using the collision technique and evaluating nerve integrity using a conduction velocity distribution (CVD) estimator is discussed in this paper. This study is aimed at improving current diagnostic techniques used for assessing carpal tunnel syndrome (CTS). Current nerve conduction studies are influenced by the activity of...
A technique for selectively activating nerve fibers based on their diameter using the collision technique and evaluating nerve integrity using a conduction velocity distribution (CVD) estimator is discussed in this paper. This study is aimed at improving current diagnostic techniques used for assessing carpal tunnel syndrome (CTS). Current nerve conduction studies are influenced by the activity of...
Studies examining traumatic brain injury have suggested a 'window of opportunity' exists for therapeutic agents to mitigate edema and cellular toxicity effectively. However, successful therapy also relies on identifying the extent of blood-brain barrier disruption, which is associated with excessive extra-cellular concentrations of ions, excitatory amino acids, and serum proteins. The following study...
Studies examining traumatic brain injury have suggested a 'window of opportunity' exists for therapeutic agents to mitigate edema and cellular toxicity effectively. However, successful therapy also relies on identifying the extent of blood-brain barrier disruption, which is associated with excessive extra-cellular concentrations of ions, excitatory amino acids, and serum proteins. The following study...
This paper introduces Neurodevelopmental Engineering, a new interdisciplinary research area at the intersection of developmental neuroscience and bioengineering. Specifically, it presents current results of the design and development process of a set of instrumented toys equipped with a variety of sensors for behavioral analysis of infants in minimally structured environmental conditions. First the...
This paper introduces Neurodevelopmental Engineering, a new interdisciplinary research area at the intersection of developmental neuroscience and bioengineering. Specifically, it presents current results of the design and development process of a set of instrumented toys equipped with a variety of sensors for behavioral analysis of infants in minimally structured environmental conditions. First the...
Recognizing abnormal breathing activity from body movement is a challenging task in machine vision. In this paper, we present a non-intrusive automatic video monitoring technique for detecting abnormal breathing activities and assisting in diagnosis of obstructive sleep apnoea. The proposed technique utilizes infrared video information and avoids imposing geometric or positional constraints on the...
Recognizing abnormal breathing activity from body movement is a challenging task in machine vision. In this paper, we present a non-intrusive automatic video monitoring technique for detecting abnormal breathing activities and assisting in diagnosis of obstructive sleep apnoea. The proposed technique utilizes infrared video information and avoids imposing geometric or positional constraints on the...
With the introduction of microarray, cancer classification, diagnosis and prediction are made more accurate and effective. However, the final outcome of the data analyses very much depend on the huge number of genes with relatively small number of samples present in each experiment. It is thus crucial to select relevant genes to be used for future specific cancer markers. Many feature selection methods...
With the introduction of microarray, cancer classification, diagnosis and prediction are made more accurate and effective. However, the final outcome of the data analyses very much depend on the huge number of genes with relatively small number of samples present in each experiment. It is thus crucial to select relevant genes to be used for future specific cancer markers. Many feature selection methods...
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