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To better simulate RF field behavior in the human head for MRI applications, dyadic Green's function (DGF)/method of moment (DGF/MOM) -based solutions of the electromagnetic field (EMFs) inside a head-sized, stratified sphere in different MRI coils are presented. The lossy, multilayered spherical head phantom has similar radial conductivity and permeability profiles as human head and is loaded in...
We propose a novel magnetic resonance electrical impedance tomography (MREIT) algorithm, RBF-MREIT algorithm and apply it to reconstruct the conductivity distribution of human head. Computer simulations are conducted on a three-sphere head model to test the feasibility of the proposed algorithm. The simulation results demonstrate that the RBF-MREIT algorithm can estimate the conductivity values within...
We have developed a new magnetic resonance electrical impedance tomography (MREIT) algorithm, RSM-MREIT. This new algorithm uses response surface methodology (RSM) and Simplex method to reconstruct subject's conductivity distribution. RSM-MREIT algorithm uses only one component of the measured magnetic flux density to reconstruct the conductivity images, and, consequently, solves the rotation problem...
Functional imaging has played a significant role in bettering our understanding of mechanisms of brain function and dysfunctions. We review recent research on electrophysiological neuroimaging, multimodal neuroimaging integrating functional MRI with EEG, and our development of magnetoacoustic tomography with magnetic induction for high resolution impedance imaging. Examples from research of our group...
The coil separation of phased-array coils is an important issue if a wide area of interest is to be imaged. An equivalent circuit of two circular-shaped coils was used to compute the optimal distance in a two phased-array coil. This circuit included the mutual inductance of two circular coils. An expression for the mutual inductance was derived and the resulting values included in the circuit. With...
In studying bioelectromagnetic problems, finite element method offers several advantages over other conventional methods such as boundary element method. It allows truly volumetric analysis and incorporation of material properties such as anisotropy. Mesh generation is the first requirement in the finite element analysis and there are many different approaches in mesh generation. However conventional...
In the last decade, the possibility to noninvasively estimate cortical activity and connectivity has been highlighted by the application of the techniques known as high resolution EEG. These techniques include a subject's multi-compartment head model (scalp, skull, dura mater, cortex) constructed from individual magnetic resonance images, multi-dipole source model, and regularized linear inverse source...
This paper presents T2-MRI as a very promising method to investigate the pathophysiology of electrical shock injuries, permitting distinction between thermal and electroporation damaged tissue and permitting monitoring of the therapeutic efficacy of membrane sealing surfactants
We have recently introduced the concept of whole-body asymmetric MRI systems. In this theoretical study, we investigate the PNS characteristics of whole-body asymmetric gradient systems as compared to conventional symmetric systems. Recent experimental evidence supports the hypothesis of transverse gradients being the largest contributor of PNS due to induced electric currents. Asymmetric head gradient...
Imaging looks inside the patient's body, exposing the patient's anatomy beyond what is visible on the surface. Medical imaging has a very successful history for medical diagnosis. It also plays an increasingly important role as enabling technology for minimally invasive procedures. Interventional procedures (e.g. catheter based cardiac interventions) are traditionally supported by intra-procedure...
In patient-specific cardiac information recovery, meaningful a priori models for constraining the sparse and noise-corrupted measurements, and also the optimal criteria for coupling them together, are essential for obtaining more reliable estimates. Although the extensively used biomechanical models give promising results, it cannot account for the active components of the myocytes. In view of this,...
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