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The response of the metabolic network of human red blood cell is investigated using the E-Cell simulation system when pyruvate kinase (PK) is deficient. The results that several downstream metabolites of the glycolysis pathway accumulate are in a good agreement with experimental data reported in literatures. This accumulation results in the reaction that phosphoglycerate kinase (PGK) catalyzes reversing...
In this study, the relationship between physiological parameters and electrical impedance changes of human blood and their further clinical implications are investigated. The study is performed on 255 erythrocyte suspension samples derived from 51 male donors. The samples are stored at 4degC and measurements are done on the (0th, 10th, 21st, 35th and 42nd days of storage. The complex impedance is...
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