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Alteration of neuron structure can induce abnormalities in signal propagation for nervous systems, as seen in traumatic brain injuries, damage and tumours. Here, effects of geometrical changes and damage of neuron structure are investigated in two scaled nerve bundle models, made of myelinated and unmyelinated nerve fibres. We propose a 3D finite element model of a nerve bundle as a unique framework...
This paper reports on the design and optical characterization of a single laser to multiple optical fiber (SLMOF) device for optogenetics research. Output end of SLMOF is an optical fiber bundle made by 210 optical fibers arranged into a 7×30 matrix. Single laser beam produced by laser diode (LD) is delicately steered on optical table to be coupled into target optical fiber. By controlling the power...
Infrared neural stimulation (INS) provides a contact free, high spatial resolution method to regulate neural activities. Due to photothermal effect, neurons which located in the beam path, could be depolarized by infrared light. How to keep the high efficiency of opto-thermal transduction in nerve tissue, and meanwhile increase the photon penetration depth in untargeted tissues is the key question...
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