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Both treadmill training and epidural stimulation can help to reactivate the central pattern generator (CPG) in the spinal cord after a spinal cord injury. However, designing an appropriate training approach and a stimulation profile is still a controversial issue. Bearing the Hebbian theory in mind, one can speculate a relation between the number of input afferent signals and the quality of movement...
The fundamental role of the cerebellum in motor learning explains the deficits of cerebellar patients in adaptation to a changing environment. For example, lesions to the cerebellar cortex compromise performance during tasks like reaching a target under a force field perturbation. However, the exact relationship between neural damages and misbehaviors still needs to be clarified. To this aim, it could...
Many real-time brain-machine interface (BMI) applications require quickest detection of abrupt changes in observed neural signals in an online manner. In the presence of multi-neuronal recordings, we propose both model-based and model-free approaches to detect the change in neuronal ensemble spiking activity. The model-based approach is motivated from state space modeling and recursive Bayesian filtering...
Epiretinal prostheses have been reported to restore partial visual function of patients suffering from retinal degenerative diseases. The design of stimulating electrode array of the epiretinal prosthesis is one of the pivotal factors to influence its performance and spatial resolution. Because the cell density distribution of retinal ganglion cells(RGCs) and retinal anatomic structure varied with...
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