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This paper presents a methodology for running NGS read mapping tools in the cloud environment based on the MapReduce programming paradigm. As a demonstration, the recently developed and robust sequence alignment tool, BFAST, is used within our methodology to handle massive datasets. The results of our experiments show that the transformation of existing read mapping tools to run within the MapReduce...
DNA Microarray is an innovative tool for gene studies in biomedical research, and its applications can vary from cancer diagnosis to human identification. In microarray experiment, the gene expression process is divided into three basic steps: gridding, segmentation, and quantification. For processing of microarray images, a new, automatic, fast and accurate approach is proposed for gridding noisy...
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