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This study aimed to provide quantitative clinical data on the comparison of the effect of talking on both manual and automatic blood pressure (BP) measurements. Manual auscultatory systolic and diastolic blood pressures (SBP and DBP) were obtained from 20 healthy subjects under resting and talking conditions. During the measurement the oscillometric cuff pressure was also recorded digitally. Manual...
Heart failure (HF) is a kind of serious cardiovascular diseases, leading to an increasing burden imposed on public healthcare. Early diagnosis and proper treatment of HF are essential to reducing its morbidity and mortality. In spite of the implementation of clinical guidelines for HF, early recognition and stratification of HF risk remain unsolved. In this work, we supposed a computational model...
We estimate that as much as 5% of all recorded ECGs worldwide may, to some degree, suffer from poor signal quality or incorrect electrode positioning, which often interferes with correct interpretation of the ECG. Proper training of ECG technicians and regular inspection of signal quality is necessary to achieve a high standard. Due to the large amounts of ECGs recorded daily, we devised an automatic...
Medical cooperation with clinical centers of Balkan Countries was developed by the “G. Pasquinucci” Heart Hospital of “G. Monasterio” Foundation in Massa, with the support of the “Heart World” Association and the Tuscany Region, in diagnosis and care of congenital heart malformations. Given the geographical scenery it was important to set up a tele-consulting network over the Internet for multi-center...
This study was to investigate the diagnosis of DSCT pre-operation about the left ventricular function in complex congenital heart disease with diminished pulmonary blood flow in comparison of 2D-echocardiography. 50 patients scheduled for operation because of suspected or definited complex congenital heart disease with diminished pulmonary blood flow were examined by DSCT. The images were quantitatively...
Cardiac fibrillation is a complex arrhythmia whose mechanisms of onset, maintenance and interruption are not completely understood. Fibrillatory processes have usually been considered as random phenomena without any apparent coordinated pattern. However, recently developed experimental and human studies have demonstrated that a hierarchical activation may govern some fibrillatory processes. In this...
Engraftment of viable, electrically functional cells into a myocardial infarct as a method for restoring functionality is currently a topic of active research interest. Cells implanted in this way can form gap junction connectivity with each other, but often do not connect well with the surrounding tissue outside the infarct. Using a bidomain computer simulation model, we find that activation of these...
The aim of this paper is to discuss the main characteristics of a system created to study, in a community, the evolution of people suffering cardiac disease or people prone to suffer it. The system has two main components: a portable device for ECG acquisition, henceforth Recorder, and Windows-compatible software, named Analyzer, to storage and study the signals acquired by the recorders. The Register...
The aim of Electrocardiographic (ECG) inverse problem is to use the measured ECG signals on the body surface to noninvasively reconstruct the activity of heart. Due to the ill-posedness, the solution of ECG inverse problem needs employ as much prior information about the cardiac activities as possible. In this study, the spatial sparse performance of the transmembrane potential (TMP) was investigated...
Myocardial scar is the most common substrate for malignant arrhythmia and cardiac arrest. Radiofrequency ablation, as one of the emerging mainstream therapies, currently relies on electrophysiologic (EP) map acquired on endocardial and occasionally epicardial surfaces. As myocardial scar is often complex with shapes varying with the depth of the myocardium, endocardial and epicardial maps may differ...
Modern QRS detectors in patient monitoring systems must provide accurate results even when interfering noise is present. This task is complicated by the heterogeneous and non-uniform nature of the patient population. Certain beat morphologies demand a significant increase in the complexity of beat detection algorithms. At the same time, it is important to take a system-wide approach to the beat detection...
Congenital heart disease is the most common cause of death in infants. Three-dimensional echocardiography may provide reliable information than two-dimensional methods. The purpose of the study was attempted to evaluate the feasibility and accuracy of the 3D echocardiographic virtual endoscopy in Atrial Septal Defect (ASD). An improved fuzzy C-means clustering algorithm brFCM was adopted to accelerate...
In this paper we have used the most useful processing and analysis methods to classify two congenital heart defects. The most important congenital valve disease is the congenital aort stenosis(AS) and of septum diseases is Ventricular Septal Defect(VSD). In this research, we managed to fuzzy classification of three groups of healthy, and AS, and VSD patients with the use of PCG.
Ejection fraction and microvolt T-wave alternans (mTWA) lack specificity to predict sudden cardiac death in heart failure (HF). We compared resting ECG variables (QRS duration, lead-dependent T-amplitudes) and exercise-ECG-derived TWA variables (amplitude in the 12 leads, in the orthogonal X, Y, Z leads and in the vector magnitude) of 56 HF patients with an implanted cardioverter-defibrillator: cases...
In this study, we present a framework to simulate multi-scale wave propagation of ischemia which leverages the high-performance computing capacity of Graphic Processing Units (GPU). To cope with the no-flux boundary condition and address the branch deficiency, a phase-field method is employed. An on-the-fly visualization method of two dimensional simulation results is proposed. A fusion volume visualization...
Radiofrequency catheter ablation (CA) is increasingly employed to treat atrial fibrillation (AF), yet selection of patients who would actually benefit from this therapy still remains an open issue. The present work introduces some non-invasive quantitative parameters to discriminate between successful and failing CA procedures by exploiting the spatial diversity of the 12-lead surface ECG. They are...
The aim of the study was to design and evaluate a coupler/microphone system for recording weak murmurs from stenoses in the coronar artery. The suggested design is based on the use of a high quality microphone, coupled to the chest through a small air cavity. Since the determination of the exact frequency range of interest related to murmurs is part of the purpose of the study, one of the goals of...
Asynchronous activation of the ventricles deteriorates cardiac function acutely, followed by further worsening over time. In a multi-scale model we tested the hypothesis that the second phase is due to mechano-electrical coupling (MEC), mediated by remodeling of ionic membrane currents. Our model describes hemodynamic interaction between the left and right ventricle as well as mechanical interaction...
The variation of the hydrodynamic parameters of the coronary artery is researched while the elastic property of the blood vessel and the effect of the heart muscle are considered. The coronary artery with geometry branches is reconstructed using the software Mimics based on the clinical detection of CT images of coronary angiography. Spring elements connected the vascular wall are used to simulate...
In this paper, we present a novel algorithm for pediatric heart sound segmentation, incorporated into a graphical user interface. The algorithm employs both the Electrocardiogram (ECG) and Phonocardiogram (PCG) signals for an efficient segmentation under pathological circumstances. First, the ECG signal is invoked in order to determine the beginning and end points of each cardiac cycle by using wavelet...
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