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Geographic Atrophy (GA) of the retinal pigment epithelium (RPE) is an advanced form of atrophic age-related macular degeneration (AMD) and is responsible for about 20% of AMD-related legal blindness in the United States. Two different imaging modalities for retinas, infrared imaging and autofluorescence imaging, serve as interesting complimentary technologies for highlighting GA. In this work we explore...
Low back pain is associated with dysfunction in recruitment of muscles in the lumbopelvic region. Effective rehabilitation requires preferential activation of deep stabilizing muscle groups yet training these muscles poses challenges in a clinical setting. This study was carried out in order to quantify the response of deep stabilizing muscles (transverses abdominis and deep fibres of multifidus)...
There is a need for objective tools to help clinicians to diagnose Alzheimer's Disease (AD) early and accurately and to conduct Clinical Trials (CTs) with fewer patients. Magnetic Resonance Imaging (MRI) is a promising AD biomarker but no single MRI feature is optimal for all disease stages. Machine Learning classification can address these challenges. In this study, we have investigated the classification...
We examined surface electromyogram (EMG) characteristics during voluntary isometric activation of the first dorsal interosseous (FDI) muscle in stroke survivors. Five stroke subjects participated in the study. They were instructed to generate isometric contraction at different force levels. The recording was performed in both paretic and contralateral muscles using a matched force protocol. Comparisons...
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