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Lung cancer is the leading cause of cancer deaths worldwide. Many studies have investigated the carcinogenic process and identified the biomarkers for signature classification. However, to the best of knowledge, there is no satisfactory network-based method for carcinogenesis characterization and diagnosis from the systems perspective. In this study, a systems biology approach, which integrated microarray...
Aging, an extremely complex and system-level process, has attracted much attention in medical research, especially since chronic diseases are quite prevalent in the aged population. These may be the result of both gene mutations that lead to intrinsic perturbations and environmental changes that may stimulate signaling in the body. In addition, aging may result in diminished homeostasis and increased...
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