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Small calibre (<;;6mm) polytetrafluoroethylene (PTFE) bypass grafts have poor medium and long term patency due to the development of neointimal hyperplasia at the distal anastomosis. The inelasticity of PTFE is implicated in this mechanism of failure. We have developed a novel polyhedral oligomeric silsesquioxane (POSS) nanocage incorporated into a poly(carbonate)urethane (PCU) biomaterial with...
In the past, the reduced availability and problems with the preservation/storage limited the use of cryopreserved /defrosted arteries (cryografts) in lower limb revascularization procedures. However, the recent development of cryopreservation techniques enhanced cryografts availability and value, and renewed the interest in their use as vascular substitutes. Anyway, some issues related with the cryografts...
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