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MicroRNAs (miRNAs) are small noncoding RNAs which regulate gene expression. In this research, we used the Multiz alignments data of 44 Vertebrates to retrieve syntenic homolog sequences. And we identified 37 members of miR-1302 family among 71 potential homolog sequences. Then we analyzed the 37 homologs of hsa-mir-1302s by RepeatMasker and found all of these sequences are derived from MER53 elements...
Propose: Idiopathic orbital inflammatory pseudotumors (IOIP) are inflammatory pseudotumors (IPT) of unknown etiology that develop in the orbit. Due to the lack of well-defined pathogenic mechanisms and diagnostic markers, diagnosis and treatment of this disease remain a significant challenge. Therefore, the aims of this study are to define the etiological factors of IOIP and to identify potential...
Due to involvement in changing of chromatin structure, histone modifications are very important in regulation for gene expression. Some attempts have been done to resolve the relationship among histone modifications and gene expression. In this study, four types of Bayeasian network methods, Maximum weight spanning tree (MWST), K2, Markov Chain Monte Carlo (MCMC) and greedy-search(GS), are used to...
Reactive oxygen species (ROS) and activation of redoxsensitive transcription factors such as nuclear factor (NF)-κB have been implicated in pro-inflammatory responses induced by nanoparticles. However, there is still only little knowledge about the pro-inflammatory responses induced by multi-walled carbon nanotubes (MWCNTs). The objective of the present study was to compare the ability of MWCNTs and...
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