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Marine water quality model is complicated because of its multi-parameter and multi-response characteristic. In this paper, a new method based on data-driven model (DDM) is developed to retrieve the value of model parameters for model calibration. All training data are calculated by numerical water quality model from results of multi-parameter matching design cases. The basic idea is to find out the...
A discrete mathematical model with time delays for the transmission of malaria is established. The basic reproductive number R0 of the model is defined. Numerical simulations are given to show that the disease free equilibrium is stable when R0<;1 and the unique positive equilibrium is locally asymptotically stable when R0 > 1. The elasticity of the basic reproductive number with respect to...
Membrane protein and its interaction network has become a novel research direction in bioinformatics. Multiple researches on these interactions can improve our understanding of diseases and provide the basis to revolutionize therapeutic treatments. In this paper, a novel membrane protein interaction network simulator is proposed for system biology studies by intelligent multi-agents method. We consider...
During the past decades, construction and demolition (C&D) waste has received increasing attention from construction practitioners and researchers around the world. A plethora of research has been published in various academic journals. These studies have investigated a wide range of topics under the umbrella of C&D waste management, of which investigation into the generation of C&D waste...
The quantity of available water resources have been recognized as limiting factors in development of most of the arid regions. Therefore, sustainable use of water resources is key problem for development of these areas. In the present paper, Hetao irrigation district, one of the largest irrigation districts in the Yellow River basin, is selected as the research area. The sustainable utilization coupled...
Numerical simulation was established and validated by the course of the rainstorm following 25 hours, which shows that the flow field can help to make the water in pre-dam effuse and prevent the Dianchi Lake water from recharging. Soluble reactive phosphorus (SRP) elimination was calculated along the whole rainfall. The result shows that the simulation is identical to the calculated and is able to...
Liver failure is a serious disease which mortality rate is up to 70%. During the past decades, several attempts have been made to develop bioartificial liver systems (BAL) capable of providing temporary hepatic support to patients with liver failure. The bio-reactor is the core of the bioartificial liver system, which exists within the complex fluid dynamics problems. In recent years, with the rapid...
The protein folding problem is a central issue in Bioinformatics. It still represents a challenge for both Biology and Computer Science. Proteins are composed by up to hundreds of amino acids, each one with tenths of atoms. In general, a full representation of such structure and its interacting elements precludes computational simulations. This work proposes a molecular model for representing protein...
System biology is one of the leading edge cross-subjects which requires the cooperation between computer science and biological science. Abstracting complex life phenomenon, like metabolic or transcription regulation pathway, into networks to simulate these processes is one of the hotspots in System biological research. In this paper, we construct a network to simulate one of the most concerned areas...
The bio-hydrogen producing process has complex interactions; thus, constructing a detailed mechanistic model and proper control architecture is difficult. Artificial neural networks (ANNs) are capable of inferring the complex relationships between input and output process variables without a detailed characterization of the mechanisms governing the process. This work presented a novel ANN that accurately...
In this paper, we propose a computer simulated biopsy marking (CSBM) system for gastroscopy physicians. The purpose of the study is to solve two problems: how to mark suspicious areas for follow-ups without hurting stomach, and how to cut down time spent on gastroscopy. By constructing a three-dimensional (3D) virtual stomach model and using a tracking device, the position of gastroscope is shown...
Generally,the bursting firing pattern of action potential has higher transmission efficiency compared with the consecutive firing pattern in the same average frequency condition.Recently,some articles about the synapse short-term plasticity have shown that there are different mechanism to form short-term plasticity in different presynaptic firing frequency condition probably.This makes us to question...
Highway green landscape is an important part of the highway systems. Now freeway and multi-lane highway green landscape have been concerned, but two-lane highway green landscape has not been researched. Through analyzing the function of greening, this paper summarizes a research project that was to develop evaluation models for green landscape evaluation. The main evaluation indices considered are...
In the field of healthcare building design, there are two significant focuses on Eco-effective design (EED) and Evidence-based design (EBD). Regarding the indoor air quality for occupants' health, EBD may conflict with EED goals. This research proposed a Healthcare and Sustainable Parametric Method (HSPM) incorporating Building Information Modeling (BIM) and then used this method to a design project...
We present an individual agent-based model of transcription factor binding to DNA. We explicitly represent every single transcription factor and every single binding site in our simulation. In order to obtain statistically significant results from our model, it is necessary to perform a large number of simulations. This has previously been hampered by the computational demands of individual agent-based...
The drag due to the vegetation affects of pollutant dispersion as it flows through vegetation. The previous research has aimed mostly at a cylinder-based model in which the vertical vegetative characteristics are homogenous. It rarely mentions natural vegetation in which the vertical vegetative characteristics undergo steep changes. Based on the laboratory measurements and observations, an empirical...
In this paper, the characteristics of organic pollutants in the study area are analyzed on the basis of the analysis of three field water samples. Then based on the parameters obtained from laboratory test and domestic and foreign literature, trichloroethylene (TCE) and perchloroethylene (PCE) transported in the groundwater of the study area are simulated using Groundwater Modeling System (GMS). The...
An X-ray computed tomography (CT) simulator based on Geant4 toolkit was developed for simulation of both fan- and cone-beam CT scanners. There major components X-ray tube, phantom and detector are simulated. Different to analytical simulation, this simulation is accordance with imaging physics by adopting the Geant4 toolkit. Compared with ordinary statistical simulation, acceleration investigation...
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