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Since there are several applications of Electrical Bioimpedance (EBI) that use the Cole parameters as base of the analysis, to fit EBI measured data onto the Cole equation is a very common practice within Multifrequency-EBI and spectroscopy. The aim of this paper is to compare different fitting methods for EBI data in order to evaluate their suitability to fit the Cole equation and estimate the Cole...
Cardiotocography (CTG) is a frequently used technique of fetal monitoring to evaluate the well being of the fetus during pregnancy and in labor. The surveillance technique depends on the analysis of characteristic fetal heart rate patterns and uterine contractions. Computerized analyses can mitigate the intra-observer and inter-observer variability of visual CTG recording explanation, decrease the...
Neural amplifiers require a large time-constant high-pass filter at ~1 Hz to reject large DC offsets while amplifying low frequency neural signals. This high pass filter is typically realized using large area capacitors and teraohm resistances which makes integration difficult. In this paper, we present a novel topology for a neural amplifier which exploits the (1/f)n power spectra of local field...
Electrotonic interactions in cardiac tissue have been shown previously to modulate dynamical properties of the myocardium such as action potential duration (APD) and action potential duration restitution. A recent computational study indicated that these electrotonic effects may be strongest in small murine hearts. In the present study, we investigate experimentally how APD is modulated by activation...
The knowledge and prediction of the behavior of electrically activated muscles are important requisites for the movement restoration by FES in spinal cord injured subjects. The whole parameter's identification of a physiological musculoskeletal model for FES is investigated in this work. The model represents the knee and its associated quadriceps muscle. The identification protocol is noninvasive...
Radiation therapy (radiotherapy) is the medical use of ionizing radiation as part of cancer treatment to erradicate malignant cells. Normal tissue tolerance is currently a major dose-limiting factor. As molecular oxygen plays a critical role in creating the radiation damage, we propose a novel approach, that is, the use of acoustic radiation force (ARF) to suppress the normal tissue oxygenation, for...
This research proposes a PVDF film pulse wave sensor for use in driver's drowsiness detection. The sensor non-intrusively measures heart pulse wave from driver's palm and an adaptive filter is employed to cancel the measurement noise aroused by the changing of gripping force. Experimental results show clear pulse wave signals can be obtained. Two-hour driving simulation is performed for drowsiness...
The pulmonary function test (PFT) is used to evaluate and monitor respiratory function. The PFT is critical for the care of patients having cystic fibrosis (CF) and adjusting their clinical treatments. We analyzed the percent predicted value of forced expiratory volume in one second (FEV1%) from PFT of CF patients collected four times a year from 1966. Longitudinal FEV1% for each patient was fitted...
This paper reports changes in the spectral powers of finger photoplethysmographic waveform variability (PPGV) following hemodialysis compared to pre-dialysis. The results are based on data collected from 12 hemodynamically stable patients having regular hemodialysis thrice weekly. Six minutes of continuous electrocardiogram (ECG) and finger infra-red photoplethysmographic (PPG) signals were collected...
Implantation prediction of in-vitro fertilization (IVF) embryos is critical for the success of the treatment. In this study, support vector machine (SVM) method has been used on an original IVF dataset for classification of embryos according to implantation potentials. The dataset we analyzed includes both categorical and continuous feature values. Transformation of categorical variables into numeric...
Discrimination of murmurs in heart sounds is accomplished by means of time-frequency representations (TFR) which help to deal with non-stationarity. Nevertheless, classification with TFR is not straightforward given their large dimension and redundancy. In this paper we compare several methodologies to apply principal component analysis (PCA) to TFR as a dimensional reduction scheme, which differ...
In order to minimize infection risks of patients with artificial hearts, wireless data transmission methods with electromagnetic induction or light have been developed. However, these methods tend to become difficult to transmit data if the external data transmission unit moves from its proper position. To resolve this serious problem, the purpose of this study is to develop a prototype wireless data...
Manually detecting gait events by visual inspection of gait data is laborious. Currently, there are no robust techniques available to automate the process. However, detecting gait events is essentially a classification problem; an application for which wavelet analysis, a multiresolution technique, is well suited for. We employ wavelet analysis to classify heel strike- and toe off events using the...
Sleep staging is one of the most important tasks on the context of sleep studies. From more than 40 years the gold standard to the characterization of patient's sleep is the use of the rules proposed by Rechtschaffen and Kales (R&K). However this method has the limitation of the unnatural assignment of discrete stages instead of doing it in a continuous manner. As part of a more general framework,...
Deep brain stimulation (DBS) of the thalamus is widely used in humans to treat essential tremor and tremor dominant Parkinson's disease. After DBS lead implantation, tremor is often reduced even without electrical stimulation. Often called ldquomicrothalamotomyrdquo effect, the exact mechanism is unknown, although it is presumed to be due to micro lesioning. Here, we tested whether microthalamotomy...
One of the more interesting applications of electrotherapy involves its use in the treatment of visual disease; including retinitis pigmentosa, diabetic retinopathy and macular degeneration. The therapeutic efficacy of electrotherapy is highly dependent upon the incorporation of appropriate design choices for both the electrotherapeutic device and treatment protocol. Electrotherapeutic design drivers...
Previous research has shown that a novel form of neuro-muscular electrical stimulation (NMES) can be used to bring about aerobic training effects in sedentary adults and in patients with heart failure. However, it is not clear whether this form of NMES could induce a significantly strong cardiovascular exercise effect in a more active group where a greater stimulus is required for training. In this...
The Infrared images have been applied in clinical diagnoses, but the images are noisy and blurred. Therefore the smooth processing that can keep edges is needed. Traditional smoothing methods have the common defect that they smooth not only the noise region but also the edges. AMSS (affine morphological scale space) algorithm can be used to better save the edge information, it has the Partial Differential...
The clinical use of high frequency alternating current (HFAC) to block nerve conduction in peripheral nerves is limited due to the large volley of nerve activity generated at the initiation of HFAC. This ldquoonset responserdquo must be characterized in order to determine if it is possible to eliminate it. In this study, preliminary experiments were conducted in an in-vivo animal model using counted...
In this paper, we use EEG signals to classify two emotions-happiness and sadness. These emotions are evoked by showing subjects pictures of smile and cry facial expressions. We propose a frequency band searching method to choose an optimal band into which the recorded EEG signal is filtered. We use common spatial patterns (CSP) and linear-SVM to classify these two emotions. To investigate the time...
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