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Magnetic nanoparticles would be one of the efficient tools for the improvement of antibody-antigen reaction and the enhancement of detection signal for immunofluorescence assay (IFA). This paper focuses on the investigation of the immuno functionality of antibodies immobilized on the surface of iron oxide nanoparticles. Fe3O 4 superparamagnetic nanoparticles were successfully produced and conjugated...
Magnetite (Fe3O4) nanoparticles uniformly loaded on multi-walled carbon nanotubes (MWCNTs) were synthesized by a wet chemistry method, and then carbon coated Fe3C nanoparticles supported by MWCNTs were prepared by heat-treatments subsequently in nitrogen at 600 degC and in acetylene atmosphere at 500 degC. The as-prepared nanoparticles were all single crystals with a size distribution ranging from...
The objective of this paper is to study the therapeutic effect of nanosized As2O3/Fe3O4 complex (Fe3O4 magnetic nanoparticles containing As2O3) combined with magnetic fluid hyperthermia (MFH) on human cervical cancer Hela cells in vitro and xenograft cervical cancer in nude mice. The growth and apoptosis of Hela cells treated with nanosized As2O3/Fe3O4 complex combined with MFH was examined by MTT,...
To evaluate the biocompatibility of self-prepared Fe3O 4 magnetic nanoparticles, which has the potential application in tumor hyperthermia, MTT assay was used to evaluate the in vitro cytotoxicity; hemolysis test was carried out to estimate its blood toxicity; Fe3O4 suspended in sterile 0.9%NaCl were intraperitoneally injected into KM mouse to calculate the LD50; micronucleus (MN) were reckoned to...
Fe3O4 single crystal nanoparticles were prepared in zero field and in a magnetic field. Fe3O4 with well crystallinity is achieved in a magnetic field. X-ray diffraction, transmission electron microscopy, vibrating sample magnetometer and Mossbauer spectrum analysis have confirmed that the magnetic field results in increasing crystallinity, such as decrease surface spin disorder and cation vacancies...
Fe3O4 magnetofluid was prepared by means of a reduction in situ and coordination transformation method. The infrared spectra showed the existence of complex. Coordination stability constant and coordination number was 1.12times104 and 2.05, respectively. The X-ray diffraction results indicated that all the ferric oxide obtained was Fe3O4. The transmission electron microscope image illustrated the...
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