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In solving the question of alignment of two RNA secondary structures, it is not clear how to choose parameters for the introduction of gaps in the alignment. We introduce a Bayesian approach for aligning two RNA secondary structures. The algorithm can not only compute the optimal alignment itself but also some interesting posteriors such as posteriors of substitution matrix and gap opening penalties...
Successful biological image analysis usually requires satisfactory segmentations to identify regions of interest as an intermediate step. Here we present a novel graphical model approach for segmentation of multi-cell yeast images acquired by fluorescence microscopy. Yeast cells are often clustered together, so they are hard to segment by conventional techniques. Our approach assumes that two parallel...
Secondary structure, residue contacts and contact numbers play an important role in tertiary structure determination of proteins. In the recent past, mainly due to non local interactions, the Bayesian segmentation approach has been successfully used for secondary structure prediction. In this paper, the performance of the Bayesian segmentation approach has been enhanced by taking residue contacts...
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