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Fast processes in cardiac electrophysiology are often studied at temperatures lower than physiological. Extrapolation of values is based on widely accepted Q10 (Arrhenius) model of temperature dependence (ratio of kinetic properties for a 10degC change in temperature). In this study, we set out to quantify the temperature dependence of essential parameters that define spatiotemporal behavior of cardiac...
Cardiac tissue heterogeneities can result in spatially dependent restitution properties. We propose a method for quantifying the dispersed nature of these restitution curves (RCs) over a large number of imaged pixels/locations. Cardiac propagation in response to point stimulation was recorded in cardiomyocyte monolayers with voltage-sensitive dye over a large field of view using high resolution imaging...
Fast processes in cardiac electrophysiology are often studied at temperatures lower than physiological. Extrapolation of values is based on widely accepted Q10 (Arrhenius) model of temperature dependence (ratio of kinetic properties for a 10degC change in temperature). In this study, we set out to quantify the temperature dependence of essential parameters that define spatiotemporal behavior of cardiac...
Cardiac tissue heterogeneities can result in spatially dependent restitution properties. We propose a method for quantifying the dispersed nature of these restitution curves (RCs) over a large number of imaged pixels/locations. Cardiac propagation in response to point stimulation was recorded in cardiomyocyte monolayers with voltage-sensitive dye over a large field of view using high resolution imaging...
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