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Collagen and apatite were co-precipitated as a composite coating on poly L-lactic acid (PLLA) in an accelerated biomimetic process. The coating formed on PLLA films after 24 hours incubation was characterized. Saos-2 osteoblast-like cells were used to evaluate the cell seeding on this biomimetic composite coating. It was shown that cell seeding on PLLA films with the composite coating was greatly...
Understanding the ultra-structural response of cells to the cryopreservation process is important for designing cryopreservation strategies for cells and tissues. Cell-cell interaction and cell-scaffold interactions alter cryopreservation response and, in turn, the cellular structures involved in adhesion and intercellular contact are targets of cryopreservation-induced damage. Immuno-fluorescence...
In this study, we investigated the viscoelasticity of individual bone marrow-derived adult human mesenchymal stem cells (hMSCs), and the role of specific cytoskeletal component-F-actin microfilaments on the mechanical properties of individual hMSCs. The mechanical properties of hMSCs were determined using the micropipette aspiration technique coupled with a viscoelastic solid model of the cell. For...
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