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The feasibility of accurate prediction of physiological glucose concentration in phosphate buffered saline (PBS) solutions with a pH of 7.4, maintained at 37 degrees C, was demonstrated by applying univariate and multivariate statistical methods to their mid-infrared spectra (1500-800 cm/sup -1/). Multivariate methods, partial least squares, and principal components regression produced calibration...
The authors point out that current techniques for the quantification of blood glucose, particularly in the home environment, have lacked precision. In their investigations into the rotary effects of glucose upon the polarization vector of light, the authors have developed a polarimeter capable of microdegree precision. At the present sensitivity, normal physiological levels of blood glucose could...
Albumin, ethanol, and urea were measured in-vitro using Fourier transform infrared (FTIR) spectroscopy. The peak height and corresponding peak area of the spectra were computed for concentration prediction. This univariate method was compared with partial least squares (PLS) and principal component regression (PCR) multivariate routines. The standard errors of calibration obtained were cholesterol...
The authors derive a compartmental model for oxygen transport in vascular blood which is suitable for both steady and time-varying analysis, and which can be used with any kind of oxygen dissociation function. The derivation focuses on the establishment of expressions for the lumped convective term and the lumped oxygen dissociation function. Results of the simulation show that the value of the lumped...
Electric-field-induced surface traction (surface force density) within the red blood cell (RBC) membrane was examined. The RBC was modeled as a spheroid with a membrane of finite thickness. Surface traction within the RBC was derived using Maxwell's stress tensor. The derivation results suggested that both a compressive force and a net outward pushing force were acting on the RBC membrane. The interaction...
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