Resting State-fMRI represents an emerging and powerful tool to explore brain functional connectivity (FC) changes associated with neurologic disorders. Compared to activation/task-related fMRI, Resting State fMRI has the advantages such as (i) Blood oxygen level dependent (BOLD) fMRI signals are self-generated and independent of subject's performance during the task and (ii) a single dataset is sufficient to extract a set of resting state networks that allows to explore whole brain FC. In the experiment, 200 dynamic 3D-tomograms were taken from healthy 11 male and 9 female volunteers (aged 20–41 years) using T2 ∗ weighted echo-planar imaging method with the Philips Achieve 1.5 T MRI system SENSE-head 8 coil and TE=40 ms, deviation angle 90° with a temporal resolution of 2.64 seconds and a spatial resolution of 3.5×3.5×4 mm. This study will help to determine the various functional neurologal connections of the human brain in the resting state and use approximate spectral clustering based on a geodesic measure of similarity to define different neurological disordes created by these differences in functional neurological connections.