To be able to efficiently utilize high data rates of 100 Gbit/s and beyond, protocols must be carefully selected for specific communication parameters. At the same time, communication parameters, such as data rate/latency requirements and the channel quality, are not static. This contradiction can be solved by switching to the best suited protocol when communicationparameters change. However, replacing a protocol is a severe interference in an ongoing transmission that can easily cause performance degradation. In this paper, we present a minimal disruptive replacement approach that allows us to replace protocol implementations for an ongoing transmission.