The application of micro-blog in Ideological and political education in universities is a new subject. Therefore, it needs a systematic theoretical point of view to guide. Make a scientific analysis of the connotation, characteristics and nature of microblog and study the content, carrier form and construction method of microblog's connotation construction. This paper designed a microblog information analysis and processing flow based on Text Clustering. Firstly, the general process of text clustering was analyzed, then designed the microblog information preprocessing flow. Besides, the implementation of microblog information analysis based on text clustering was discussed. This paper implements the whole clustering related workflow.