Fast mechanical waves following e.g. electromechanical activation and aortic valve closure (AVC) have been imaged using 2D diverging waves (DW). However, their full characterization requires multiple 2D recordings in subsequent heartbeats. Given the heart cycle variability and short-lived nature of these waves, temporal alignment is challenging. Moreover, clinical matrix arrays hinder the straightforward implementation of DW, due to sub-aperture (SAP) beam forming. We have recently proposed a sparse DW sequence capable of imaging a 70°x70° volume in a clinical system and reported its preliminary validation in vivo against 2D Tissue Doppler Imaging (TDI). Herein, the feasibility of measuring fast mechanical events in 3D in vivo was investigated.