Aiming at the problem of the effect of information technology and its impact on the performance of the manufacturing industry. Based on the existing research, we sets information hardware and software investment as explanatory variables, the number of highly educated employees as the moderator variables, the enterprise performance as the explanatory variables. This paper makes an empirical study of listed companies in manufacturing industry, the result shows that informationization hardware investment has a positive impact on enterprise performance, informationization software investment has a negative effect on enterprise performance. Besides, high degree employees will play a positive role in moderating the relationship between informatization hardware capital and enterprise performance, promote the positive effect on performance. On the contrary, the high degree employees plays a negative moderating role in the relationship between capital and enterprise information software performance, reduce the negative impact on the company's performance, so the highly educated staff affects the enterprise performance from the two path, and eventually promote to improve the performance of the company.