In the recent years, artificial neural network have been used to improvement of system identification. The performance of neural network directly depends on the hidden layer, which include weights and activation functions of the network. In addition Genetic Algorithms are used to learn of neural network as a type of evolutionary computing algorithms. In this paper, the structure of hidden layers and weights are modified by using biological neuron model of Izhikevich. These two methods, Genetic Algorithms and biological model of neuron, merge together for designing a novel structure.