Advances in biomedical circuits and systems are essential technology drivers in addressing critical societal needs to increase the effectiveness and reduce the cost of healthcare. This session highlights the latest circuit innovations that contribute to advances in medical devices, sensing and imaging. For implantable and unobtrusive devices, ultrasonic power delivery and telemetry, and improved neural sensing and stimulation are addressed. Advanced medical sensing increasingly combines multiple modalities in a single device, several examples of which are also featured in this session. Finally, circuit innovations enabling improved ultrasonic and magnetic resonance imaging and optical spectroscopy are presented.