In this paper are presented the results regarding the design and the implementation of a efficient delta encoder that is intended to be used for conditioning of signals from analogue sensors. In addition is proposed a dedicate circuit architecture for transmission of digitally encoded signals from sensors to remote measurement systems using a very reliable communication media that is represented by the optical fiber. The advantage of a reduced bit rate generated by the delta encoder correlated with the intrinsic advantages of the optical fibers, especially the immunity to electric perturbations, leaded to a attractive implementation solution for a conditioning interface that can be used in complex acquisition and measurement systems. Also, the proposed delta encoder and the fiber optic based transmission system can be used in didactical laboratories for teaching advanced communication techniques.