In order to overcome some shortcomings of realizing image processing using traditional DSP programming, such as long development time, low efficiency, complex, not universal system, irregularities and other issues, this paper puts forward a solution of taking TMS320DM642's TI chip as the development platform and adopting RF5 (Reference Framework 5) to realize multi-wavelet image fusion. Through this solution, we can load, fuse, and display the images that have been registered and transformed by multi-wavelet. The authors comprehensively utilize Matlab/Simulink software, CCS4.0 (embedded software tools, connection) platform, to achieve the design and development of DSP multi-wavelet image fusion system by means of automatically generating code. We implemented the fusion algorithm according to the standard of TMS320DSP algorithm and RF5, so as to realize the standardization of algorithm and software interface, which can reduce system integration tasks, shorten the development cycle, make expansion more convenient and easier.