Transmission techniques with coherent receiver that is widely employed nowadays need good channel estimation to give good transmission performance. However, there are conditions where channel information practically cannot be acquired, for example, when the channel condition is rapidly changing. Non coherent scheme without channel information is considered as the most potential scheme to combat this kind of channel condition. In this paper the combination between MC-CDMA and Differential Unitary Space Time Frequency Modulation (DUSTFM) with noncoherent detection process for downlink transmission side is analysed. The simulations result show non-coherent transmission scheme combining MIMO MC-CDMA and DUSTFM is a very potential scheme for high mobility scenario.