Remote monitoring system is a part of Internet of Thing (IoT) application whether in healthcare, logistic or even agriculture. The system consists of several nodes including wireless sensor node which is a compulsory end-device part in remote monitoring system for data acquisition and processing. This paper discusses the available design of wireless sensor node from different hardware and interfaces, comparison and reasoning of the available design for the hardware such as the microcontroller and transceiver. A propose design provided in this paper using an ARM based microcontroller for raw data processing and nRF24L01 transceiver in wireless communication