The Electron Tracking Compton Camera (ETCC) has the wide energy range (0.1–2 MeV). We upgrade the recoil electron readout circuit, and the tracking algorithm. Due to this improvement, the data acquisition rate is faster than before, and the imaging quality is increased. The performance of ETCC is checked by using the test-tube with F-18 water solution. We have developed the ETCC for new medical imaging device and succeeded in imaging the some imaging reagents. Thus, this detector has the possibility of new medical imaging.