High-input impedance voltage-mode single input, single output (SISO) universal biquadartic filter with a new approach of programmability and electronic tunability is presented. The proposed filter is implemented by an operational transconductance amplifier (OTA), whose bias current can be externally controlled by control voltage (VCON), that results in a more reliable circuit. The different types of filter functions (i.e. high pass, low pass, band pass, notch and all pass filters) can be implemented as well as its cutoff frequency and gain can be controlled by applying different control voltages (VCON) to different OTAs, where a choice can be done digitally using microcontroller or microprocessor incorporating programmable compatibility to make it more user friendly. Moreover, this proposed filter enables easy cascading in voltage mode due to its high impedance input terminal. It uses grounded capacitors and requires no resistor, which is suitable for integrated circuit fabrication. Filter's performance parameters ω0 and Q0 can be set orthogonally by considering equal value of capacitors and transconductances gm1 and gm2. No component matching condition is required. PSPICE result has been used to justify the performance of the circuit.