Two square-loop antennas for wearable applications in the 2.45 GHz (ISM) region are presented and compared. Both antennas were simulated, and then printed on flexible DuPont Kapton sheets for measurements. The standard square-loop antenna was modified by adding four circular patches to its sides in an effort to enhance performance. The new antenna is called the Quadruple Loop (QL) antenna. Simulations and measurement results show that the QL antenna demonstrated robust operation over a wider impedance bandwidth compared to that of the standard square loop antenna.