Many transition countries, known as emerging knowledge economies, can not to catch up with more advanced, matured economies. Low salaries, job insecurity, pressure to keep low cost create a work environment in many transitions economies where mobbing and burnout is common place. This paper examines the relationship between mobbing and professional burnout syndroms among knowledge workers in Poland. The study is based on a preliminary survey among 160 Polish respondents. The results of this study confirm that phenomena of mobbing and professional burnout are very common in emerging knowledge economies. Knowledge workers, female and employees of small firms are especially impacted by mobbing and burnout. Mobbing has an influence on job burnout of knowledge workers. Managers and politicians in emerging knowledge economies can benefit from our findings, by the use our conclusions, by changing regulations and companies polices.