A design approach of an integrated guidance and control of missile-borne embedded computer system is proposed in this paper, which utilizes a multi-core DSP as the central data processing unit and a FPGA as the co-processing unit. The approach takes advantages of the multi-core processor's resources, which provides a powerful hardware platform base for data processing, data transmission and complex algorithm implementation in high speed and capacity. Aiming at real-time parallel processing, this paper splits and maps the processing tasks of system to each processor core evenly in the master-slave mode.