Metamaterials represent a new paradigm in electromagnetic science and technology. They have already leaded to many unprecedented microwave applications, which may be classified in three categories: guided-wave, radiated-wave and refracted-wave applications. Control and manipulation of electromagnetic waves is at the heart of many industries from wireless communication, Internet and optical data storage to imaging and displays. Progress in these technologies places challenging demands on material properties and therefore structured electromagnetic materials. Metamaterials are a special class of structured materials. In this paper, harmonics resonance frequency of embedded CRLH-TL array has been generated and introduced. The analysis and investigation are done by a commercial software. The good agreement between the theoretical expectation and the simulation results is observed. Finally, the application of the proposed CRLH-TL array was examined in microstrip antenna design. The proposed microstrip antenna structure has been fabricated and the measured S-parameters of the proposed structure can be analyzed with network analyzer to demonstrate the excellent performance and satisfy multiband frequencies using conventional single microstrip patch antenna.