This study addresses the effects of channel estimation error and mutual interference between licensed and unlicensed systems on outage performance of reactive relay selection in unlicensed systems over independent non-identical (i.n.i) Rayleigh fading channels and under both the maximum transmit power constraint and primary outage constraint. Toward this end, power allocation for unlicensed users is first recommended to satisfy both constraints and account for channel estimation error and mutual interference. Then, we derive an exact closed-form outage probability representation for unlicensed systems to quickly evaluate this effect in key operation parameters. Various results corroborate the derived expressions and provide useful insights into system performance.