In this prototype, sensing infusion use the sensor circuit consisting of diode laser and photodiode that used to provide electrical signals to the comparator then forwarded to the microcontroller for processing into data packets. Data packets are sent via the Zigbee transmission device, after the data packet is received by the coordinator of the ZigBee, then it is processed and displayed on the GUI (graphical user interface), the results provide information about the infusion condition of patient care without having to come to the place of installation. The result prototype test show that at high event indoors (htx), the best in high ZigBee transmitter (htx) to ZigBee coordinator is 1.2 meters from the surface of the floor with a maximum distance of 49 meters. transmission throughput tests show that the greater transmission of data packets sent by the ZigBee end device to ZigBee coordinator, the greater the throughput received by the maximum limit (bandwidth) transmission on a network of 250 Kbps.