This paper proposes a generalized high power inverter scheme based on hybrid asymmetric cascaded topology with low frequency modulation index (FMI) control. Selective harmonic mitigation technique is combined with low order harmonic elimination control strategy for limiting the top 50 low order harmonics into the setting values, which reduces the size and weight of the output filter observably. The proposed inverter scheme of low FMI is suitable for high power applications. The single harmonic distortion (SHD) of low order harmonics can be restricted by different standards according to corresponding industry field.