Hypersonic vehicle is a complex systems with strong coupling, highly nonlinear, a large uncertainty. The adaptive fuzzy control method is applied to the attitude control of the longitudinal channel. Dividing the system into inner and outer cycle, the feedback control law is designed for the longitudinal channel of hypersonic vehicle. Fuzzy function is used to approach nonlinear function in the hypersonic vehicle model, and finally based on Lyapunov theory, the adaptive law of rule parameter is derived. Simulation results show that the control system can track the desired angle of attack very well, and has strong robustness in the case of a wide range of aerodynamic parameters perturbation.