Demand for innovative and patient-centered psychiatric care to alleviate stress-related and psychosomatic conditions is high in medical settings. A psychiatric treatment modality that is effective, safe and free of adverse effects is a desirable set of criteria not only from a patient's perspective, but also for clinicians providing healthcare service to patients. We present clinical results and user feedback from a case series of patients who have undertaken a course of sensory-based technology-enhanced multimodal meditation (TEMM) to therapeutically address stress-related symptoms in a psychosupportive paradigm. An impressive clinical response and overwhelmingly positive user feedback was reported, suggesting significant therapeutic benefit.