One of most important psychological repercussions associated with victims of criminal violence is Posttraumatic Stress Disorder (PTSD). In Mexico, 11 percent of the population over 18 years has experienced a crime. In particular, Ciudad Juarez has been a long-term devastated site because of drug traffic problems and the consequences related, leading the population to a hopeless sense of fear and insecurity. Based on the efficacy of virtual reality (VR) treatments for PTSD, this paper presents preliminary efficacy data in a controlled study of virtual reality treatment for PTSD for criminal violence. Twenty participants, aged between 18 and 65, diagnosed with PTSD were randomly assigned to a virtual reality prolonged exposure treatment group or an imaginal prolonged exposure treatment group. Treatment was delivered in 12, 90-minute individual sessions conducted twice a week. Five VR models were used for PTSD exposure therapy. Data confirm that VR prolonged exposure technique was effective in reducing clinical levels of PTSD, and participants reported a preference and acceptance for this innovative intervention.