Aiming at the development demand of the equipment command information system in modern war, the architecture of distributed equipment command information system Based on mobile agent is proposed. The main system components and workflows are presented in detail, as well as the migration communication of mobile agent and the system security guarantee in the system realization are analyzed in emphasis. Study indicates that the system has the quick ability of dealing with global information, it also has good flexibility, anti-destroying ability and expandability. It provides the innovative way to the development and improvement of the future equipment command information system.