This paper presents a current status of microwave dielectric spectroscopy at the cellular level for biological investigations. The convergence of microfluidic and microwave microtechnologies enables indeed the development of an innovative observation technique of the living at the micro-scale. The non-invasive and label free detection of living or dead cells in their culture medium without any contact, the possible identification of the bio-elements and the real time monitoring ability of the technique constitute major features, which are suitable for early diseases diagnostic, preliminary and personalized drugs evaluation, toward a better patient healthcare.