We present a self-adapting power management unit (PMU) for ultra-low power wireless sensor nodes. The PMU uses 1.03nF of on-chip MIM capacitance in a reconfigurable switched-capacitor network (SCN) that automatically adapts to different battery voltages for down-conversion and different harvesting sources/harvesting conditions for up-conversion. The PMU achieves 63.8% / 60.7% down-conversion efficiency at 17.9μW active mode / 12.8nW sleep mode power loading. With the adaptive down-conversion ratio, load power range is improved by 3.76× and 5.48× in sleep and active mode, respectively. We show how the proposed adaptation method enables harvesting with solar, microbial fuel cell, and thermal energy sources, increases harvesting efficiency by 1.92× and achieves the peak extraction efficiency of 99.8% for solar cell.